Shortening the duration of antibiotic therapy is associated with reduced antibiotic exposure and reduced treatment costs. As a marker of sepsis severity, Procalcitonin (PCT) can provide useful information to help guide clinical decisions regarding antibiotic therapy. In this webinar, the lead author of the 2009 ProHOSP randomized, controlled trial published in JAMA (2009 Vol 302, No. 10:1059-1066) will discuss the trial’s results on the use of PCT guidance in reducing antibiotic exposure in patients with LRTI compared with treatment based on standard guidelines. |